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Anticoagulants: Phenobarbital lowers the plasma amounts of dicumarol (title Beforehand utilised: bishydroxycoumarin) and leads to a reduce in anticoagulant action as calculated with the prothrombin time. Barbiturates can induce hepatic microsomal enzymes leading to greater metabolism and diminished anticoagulant response of oral anticoagulants (e.p